In vivo and in vitro effects of a HIF-1alpha inhibitor, RX-0047.

Dikmen, Z Gunnur; Gellert, Ginelle C; Dogan, Pakize; Yoon, Heejeong; Lee, Young Bok; Ahn, Chang Ho; Shay, Jerry W

Dikmen, Z Gunnur; Gellert, Ginelle C; Dogan, Pakize; Yoon, Heejeong; Lee, Young Bok; Ahn, Chang Ho; Shay, Jerry W.

Affiliation

Dikmen ZG; Department of Biochemistry, Faculty of Medicine, University of Hacettepe, 06100 Sihhiye, Ankara, Turkey. gunnur@hacettepe.edu.tr

J Cell Biochem ; 104(3): 985-94, 2008 Jun 01.

Article in En | MEDLINE | ID: mdl-18275063

Subject(s)

Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors; Oligonucleotides/pharmacology; Transcription, Genetic; Animals; Antineoplastic Agents/pharmacology; Cell Line; Cell Line, Tumor; Genes, Reporter; Humans; In Vitro Techniques; Inhibitory Concentration 50; Lung Neoplasms/drug therapy; Mice; Mice, Nude; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligonucleotides / Transcription, Genetic / Hypoxia-Inducible Factor 1, alpha Subunit Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Cell Biochem Year: 2008 Type: Article Affiliation country: Turkey

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