The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice.

Li, Y; Zhang, Y; Hill, J; Kim, H-T; Shen, Q; Bissonnette, R P; Lamph, W W; Brown, P H

Li, Y; Zhang, Y; Hill, J; Kim, H-T; Shen, Q; Bissonnette, R P; Lamph, W W; Brown, P H.

Affiliation

Li Y; Breast Center, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

Br J Cancer ; 98(8): 1380-8, 2008 Apr 22.

Article in En | MEDLINE | ID: mdl-18362934

Subject(s)

Anticarcinogenic Agents/therapeutic use; Genes, erbB-2; Mammary Neoplasms, Experimental/prevention & control; Mammary Tumor Virus, Mouse/genetics; Precancerous Conditions/prevention & control; Tetrahydronaphthalenes/therapeutic use; Animals; Basic Helix-Loop-Helix Transcription Factors/genetics; Bexarotene; Cell Proliferation/drug effects; Cyclin D; Cyclins/genetics; Female; Gene Expression Profiling; Homeodomain Proteins/genetics; Mammary Glands, Animal/drug effects; Mammary Glands, Animal/growth & development; Mice; Mice, Transgenic

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Tetrahydronaphthalenes / Anticarcinogenic Agents / Mammary Tumor Virus, Mouse / Genes, erbB-2 / Mammary Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals Language: En Journal: Br J Cancer Year: 2008 Type: Article Affiliation country: United States

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