Species-specific kinetics and zonation of hepatic DNA synthesis induced by ligands of PPARalpha.

Al Kholaifi, Abdullah; Amer, Abeer; Jeffery, Brett; Gray, Tim J B; Roberts, Ruth A; Bell, David R

Al Kholaifi, Abdullah; Amer, Abeer; Jeffery, Brett; Gray, Tim J B; Roberts, Ruth A; Bell, David R.

Affiliation

Al Kholaifi A; School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK.

Toxicol Sci ; 104(1): 74-85, 2008 Jul.

Article in En | MEDLINE | ID: mdl-18375545

Subject(s)

Clofibric Acid/analogs & derivatives; DNA/metabolism; Hepatocytes/drug effects; Liver/drug effects; PPAR alpha/metabolism; Peroxisome Proliferators/pharmacology; Animals; Clofibric Acid/pharmacology; Fibric Acids; Hepatocytes/metabolism; Kinetics; Ligands; Liver/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Rats; Rats, Inbred F344; Species Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Clofibric Acid / Peroxisome Proliferators / Hepatocytes / PPAR alpha / Liver Limits: Animals Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2008 Type: Article Affiliation country: United kingdom

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