Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease.

Zhang, H-J; Siu, M K-Y; Wong, E S-Y; Wong, K-Y; Li, A S-M; Chan, K Y-K; Ngan, H Y-S; Cheung, A N-Y

Zhang, H-J; Siu, M K-Y; Wong, E S-Y; Wong, K-Y; Li, A S-M; Chan, K Y-K; Ngan, H Y-S; Cheung, A N-Y.

Affiliation

Zhang HJ; Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong Special Administrative Region, China.

Placenta ; 29(6): 549-54, 2008 Jun.

Article in En | MEDLINE | ID: mdl-18440631

Subject(s)

DNA Methylation; Gestational Trophoblastic Disease/genetics; Octamer Transcription Factor-3/genetics; Placenta/metabolism; Azacitidine/analogs & derivatives; Azacitidine/pharmacology; Cell Line, Tumor; DNA Modification Methylases/antagonists & inhibitors; Decitabine; Enzyme Inhibitors/pharmacology; Epigenesis, Genetic/physiology; Exons; Female; Gene Expression Regulation, Neoplastic/drug effects; Gestational Trophoblastic Disease/metabolism; Gestational Trophoblastic Disease/pathology; Humans; Hydroxamic Acids/pharmacology; Octamer Transcription Factor-3/metabolism; Placenta/pathology; Pregnancy; Promoter Regions, Genetic; RNA, Messenger/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Placenta / DNA Methylation / Gestational Trophoblastic Disease / Octamer Transcription Factor-3 Limits: Female / Humans / Pregnancy Language: En Journal: Placenta Year: 2008 Type: Article Affiliation country: China

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