Knockdown of cytosolic 5'-nucleotidase II (cN-II) reveals that its activity is essential for survival in astrocytoma cells.

Careddu, Maria Giovanna; Allegrini, Simone; Pesi, Rossana; Camici, Marcella; Garcia-Gil, Mercedes; Tozzi, Maria Grazia

Careddu, Maria Giovanna; Allegrini, Simone; Pesi, Rossana; Camici, Marcella; Garcia-Gil, Mercedes; Tozzi, Maria Grazia.

Affiliation

Careddu MG; Dipartimento di Biologia, Università di Pisa, Via S. Zeno 51, 56127 Pisa, Italy.

Biochim Biophys Acta ; 1783(8): 1529-35, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18445485

Subject(s)

5'-Nucleotidase/metabolism; Astrocytoma/enzymology; 5'-Nucleotidase/antagonists & inhibitors; 5'-Nucleotidase/genetics; Adenoviridae/genetics; Animals; Apoptosis; Astrocytoma/pathology; Cell Line; Cell Line, Tumor; Cell Survival; Humans; Purines/metabolism; RNA Interference; Rats

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Astrocytoma / 5'-Nucleotidase Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Year: 2008 Type: Article Affiliation country: Italy

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