A small molecule enhances RNA interference and promotes microRNA processing.

Shan, Ge; Li, Yujing; Zhang, Junliang; Li, Wendi; Szulwach, Keith E; Duan, Ranhui; Faghihi, Mohammad A; Khalil, Ahmad M; Lu, Lianghua; Paroo, Zain; Chan, Anthony W S; Shi, Zhangjie; Liu, Qinghua; Wahlestedt, Claes; He, Chuan; Jin, Peng

Shan, Ge; Li, Yujing; Zhang, Junliang; Li, Wendi; Szulwach, Keith E; Duan, Ranhui; Faghihi, Mohammad A; Khalil, Ahmad M; Lu, Lianghua; Paroo, Zain; Chan, Anthony W S; Shi, Zhangjie; Liu, Qinghua; Wahlestedt, Claes; He, Chuan; Jin, Peng.

Affiliation

Shan G; Department of Human Genetics, Emory University School of Medicine, 615 Michael St, Atlanta, Georgia 30322, USA.

Nat Biotechnol ; 26(8): 933-40, 2008 Aug.

Article in En | MEDLINE | ID: mdl-18641635

Subject(s)

Enoxacin/pharmacology; MicroRNAs/genetics; RNA Interference/drug effects; RNA Processing, Post-Transcriptional; RNA, Small Interfering/genetics; Animals; Cell Line; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins/metabolism; Humans; Lentivirus/genetics; Mice; Mice, Transgenic; MicroRNAs/metabolism; RNA, Small Interfering/drug effects; RNA, Small Interfering/metabolism; RNA-Binding Proteins/metabolism; RNA-Induced Silencing Complex/metabolism; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Enoxacin / RNA Processing, Post-Transcriptional / MicroRNAs / RNA, Small Interfering / RNA Interference Limits: Animals / Humans Language: En Journal: Nat Biotechnol Journal subject: BIOTECNOLOGIA Year: 2008 Type: Article Affiliation country: United States

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