TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.

Fajardo, Otto; Meseguer, Victor; Belmonte, Carlos; Viana, Félix

Fajardo, Otto; Meseguer, Victor; Belmonte, Carlos; Viana, Félix.

Affiliation

Fajardo O; Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-Consejo Superior de Investigaciones Científicas, 03550 San Juan de Alicante, Spain.

J Neurosci ; 28(31): 7863-75, 2008 Jul 30.

Article in En | MEDLINE | ID: mdl-18667618

Subject(s)

Cold Temperature; Neurons, Afferent/physiology; Thermosensing/physiology; Transient Receptor Potential Channels/physiology; Vagus Nerve/physiology; Animals; CHO Cells; Calcium/pharmacology; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Growth Factor/pharmacology; Neurons, Afferent/drug effects; Rats; Rats, Sprague-Dawley; TRPA1 Cation Channel; Thermosensing/drug effects; Transient Receptor Potential Channels/agonists; Transient Receptor Potential Channels/antagonists & inhibitors; Vagus Nerve/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thermosensing / Vagus Nerve / Cold Temperature / Transient Receptor Potential Channels / Neurons, Afferent Limits: Animals / Humans / Male Language: En Journal: J Neurosci Year: 2008 Type: Article Affiliation country: Spain

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