Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.

Pereira, Carlos F; Terranova, Rémi; Ryan, Natalie K; Santos, Joana; Morris, Kelly J; Cui, Wei; Merkenschlager, Matthias; Fisher, Amanda G

Pereira, Carlos F; Terranova, Rémi; Ryan, Natalie K; Santos, Joana; Morris, Kelly J; Cui, Wei; Merkenschlager, Matthias; Fisher, Amanda G.

Affiliation

Pereira CF; Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom.

PLoS Genet ; 4(9): e1000170, 2008 Sep 05.

Article in En | MEDLINE | ID: mdl-18773085

Subject(s)

B-Lymphocytes/cytology; Cellular Reprogramming/physiology; DNA-Binding Proteins/metabolism; Embryonic Stem Cells/metabolism; HMGB Proteins/metabolism; Octamer Transcription Factor-3/metabolism; Pluripotent Stem Cells/metabolism; Transcription Factors/metabolism; Animals; Cell Differentiation; Cell Fusion; Cell Nucleus/metabolism; Embryonic Stem Cells/cytology; Homeodomain Proteins/metabolism; Humans; Hybrid Cells/metabolism; Mice; Nanog Homeobox Protein; Pluripotent Stem Cells/cytology; SOXB1 Transcription Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / B-Lymphocytes / HMGB Proteins / Pluripotent Stem Cells / DNA-Binding Proteins / Octamer Transcription Factor-3 / Embryonic Stem Cells / Cellular Reprogramming Limits: Animals / Humans Language: En Journal: PLoS Genet Journal subject: GENETICA Year: 2008 Type: Article Affiliation country: United kingdom

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