Mitochondrial dynamics and apoptosis: a painful separation.
Dev Cell
; 15(3): 341-343, 2008 Sep.
Article
in En
| MEDLINE
| ID: mdl-18804432
ABSTRACT
Reporting in Molecular Cell, Sheridan et al. (2008) and Breckenridge et al. (2008) show that mitochondrial fragmentation is not required to induce cell death. Meanwhile, Yamaguchi et al. show that proapoptotic Bcl-2 family members promote cytochrome c mobilization through Opa1-mediated cristae remodeling. Therefore, the connection between mitochondrial structure and apoptosis is more complex than previously imagined.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Apoptosis
/
Proto-Oncogene Proteins c-bcl-2
/
Mitochondrial Proteins
/
Mitochondria
Limits:
Animals
Language:
En
Journal:
Dev Cell
Journal subject:
EMBRIOLOGIA
Year:
2008
Type:
Article
Affiliation country:
United kingdom