The therapeutic effect of TNFR1-selective antagonistic mutant TNF-alpha in murine hepatitis models.

Shibata, Hiroko; Yoshioka, Yasuo; Ohkawa, Akiko; Abe, Yasuhiro; Nomura, Tetsuya; Mukai, Yohei; Nakagawa, Shinsaku; Taniai, Madoka; Ohta, Tsunetaka; Mayumi, Tadanori; Kamada, Haruhiko; Tsunoda, Shin-ichi; Tsutsumi, Yasuo

Shibata, Hiroko; Yoshioka, Yasuo; Ohkawa, Akiko; Abe, Yasuhiro; Nomura, Tetsuya; Mukai, Yohei; Nakagawa, Shinsaku; Taniai, Madoka; Ohta, Tsunetaka; Mayumi, Tadanori; Kamada, Haruhiko; Tsunoda, Shin-ichi; Tsutsumi, Yasuo.

Affiliation

Shibata H; Laboratory of Pharmaceutical Proteomics, National Institute of Biomedical Innovation, 7-6-8 Saito-Asagi, Ibaraki, Osaka 567-0085, Japan.

Cytokine ; 44(2): 229-33, 2008 Nov.

Article in En | MEDLINE | ID: mdl-18815054

Subject(s)

Hepatitis, Animal/drug therapy; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha/therapeutic use; Alanine Transaminase/blood; Animals; Carbon Tetrachloride/pharmacology; Cell Line; Concanavalin A/pharmacology; Cytokines/blood; Disease Models, Animal; Female; Hepatitis, Animal/blood; Hepatitis, Animal/chemically induced; Hepatitis, Animal/immunology; Humans; Mice; Mice, Inbred BALB C; Receptors, Tumor Necrosis Factor, Type I/antagonists & inhibitors; Receptors, Tumor Necrosis Factor, Type I/metabolism; Tumor Necrosis Factor-alpha/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Receptors, Tumor Necrosis Factor, Type I / Hepatitis, Animal Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cytokine Journal subject: ALERGIA E IMUNOLOGIA Year: 2008 Type: Article Affiliation country: Japan

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