An isogenetic myoblast expression screen identifies DUX4-mediated FSHD-associated molecular pathologies.

Bosnakovski, Darko; Xu, Zhaohui; Gang, Eun Ji; Galindo, Cristi L; Liu, Mingju; Simsek, Tugba; Garner, Harold R; Agha-Mohammadi, Siamak; Tassin, Alexandra; Coppée, Frédérique; Belayew, Alexandra; Perlingeiro, Rita R; Kyba, Michael

Bosnakovski, Darko; Xu, Zhaohui; Gang, Eun Ji; Galindo, Cristi L; Liu, Mingju; Simsek, Tugba; Garner, Harold R; Agha-Mohammadi, Siamak; Tassin, Alexandra; Coppée, Frédérique; Belayew, Alexandra; Perlingeiro, Rita R; Kyba, Michael.

Affiliation

Bosnakovski D; Lillehei Heart Institute and Department of Pediatrics, University of Minnesota, MN 55455, USA.

EMBO J ; 27(20): 2766-79, 2008 Oct 22.

Article in En | MEDLINE | ID: mdl-18833193

Subject(s)

Gene Expression Regulation; Homeodomain Proteins/physiology; Muscular Dystrophy, Facioscapulohumeral/pathology; Myoblasts/metabolism; Animals; Cell Differentiation; Cloning, Molecular; Gene Deletion; Glutathione/metabolism; Homeodomain Proteins/metabolism; Mice; Muscular Dystrophy, Facioscapulohumeral/metabolism; Oxidation-Reduction; PAX3 Transcription Factor; PAX7 Transcription Factor/metabolism; Paired Box Transcription Factors/metabolism; Phenotype; Transgenes

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / Homeodomain Proteins / Muscular Dystrophy, Facioscapulohumeral / Myoblasts Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: EMBO J Year: 2008 Type: Article Affiliation country: United States

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