Genomic effects of once-weekly, intramuscular interferon-beta1a treatment after the first dose and on chronic dosing: Relationships to 5-year clinical outcomes in multiple sclerosis patients.

Weinstock-Guttman, Bianca; Bhasi, Kavitha; Badgett, Darlene; Tamaño-Blanco, Miriam; Minhas, Miranda; Feichter, Joan; Patrick, Kara; Munschauer, Frederick; Bakshi, Rohit; Ramanathan, Murali

Weinstock-Guttman, Bianca; Bhasi, Kavitha; Badgett, Darlene; Tamaño-Blanco, Miriam; Minhas, Miranda; Feichter, Joan; Patrick, Kara; Munschauer, Frederick; Bakshi, Rohit; Ramanathan, Murali.

Affiliation

Weinstock-Guttman B; Jacobs Neurological Institute, Buffalo General Hospital, Buffalo, NY 14203, United States.

J Neuroimmunol ; 205(1-2): 113-25, 2008 Dec 15.

Article in En | MEDLINE | ID: mdl-18950872

Subject(s)

Genome, Human/drug effects; Immunologic Factors/administration & dosage; Interferon-beta/administration & dosage; Multiple Sclerosis/drug therapy; Adult; Chronic Disease; Cluster Analysis; Drug Administration Schedule; Female; Gene Expression/drug effects; Gene Expression Profiling/methods; Humans; Injections, Intramuscular/methods; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Multiple Sclerosis/genetics; Multiple Sclerosis/pathology; Oligonucleotide Array Sequence Analysis/methods; Time Factors; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genome, Human / Interferon-beta / Immunologic Factors / Multiple Sclerosis Type of study: Observational_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: J Neuroimmunol Year: 2008 Type: Article Affiliation country: United States

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