Acquired resistance to small molecule ErbB2 tyrosine kinase inhibitors.

Chen, Franklin L; Xia, Wenle; Spector, Neil L

Chen, Franklin L; Xia, Wenle; Spector, Neil L.

Affiliation

Chen FL; Duke University Medical Center, Department of Medicine, Division of Medical Oncology, Durham, North Carolina 27710, USA.

Clin Cancer Res ; 14(21): 6730-4, 2008 Nov 01.

Article in En | MEDLINE | ID: mdl-18980964

Subject(s)

Breast Neoplasms/drug therapy; Drug Resistance, Neoplasm; Protein Kinase Inhibitors/therapeutic use; Quinazolines/therapeutic use; Receptor, ErbB-2/metabolism; Antineoplastic Agents/therapeutic use; Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Breast Neoplasms/metabolism; Humans; Lapatinib; Models, Biological; Receptor, ErbB-2/antagonists & inhibitors; Signal Transduction/drug effects

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinazolines / Breast Neoplasms / Receptor, ErbB-2 / Drug Resistance, Neoplasm / Protein Kinase Inhibitors Type of study: Prognostic_studies Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2008 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google