Preparation of functionally preserved CD4+ CD25high regulatory T cells from leukapheresis products from ulcerative colitis patients, applicable to regulatory T-cell transfer therapy.

Sumida, Y; Nakamura, K; Kanayama, K; Akiho, H; Teshima, T; Takayanagi, R

Sumida, Y; Nakamura, K; Kanayama, K; Akiho, H; Teshima, T; Takayanagi, R.

Affiliation

Sumida Y; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Cytotherapy ; 10(7): 698-710, 2008.

Article in En | MEDLINE | ID: mdl-18985477

Subject(s)

Cell Separation/methods; Colitis, Ulcerative/immunology; Leukapheresis/methods; T-Lymphocytes, Regulatory/immunology; Adolescent; Adult; Aged; CD4 Antigens/immunology; Cell Proliferation; Colitis, Ulcerative/therapy; Female; Forkhead Transcription Factors/immunology; Forkhead Transcription Factors/metabolism; Humans; Integrins/immunology; Integrins/metabolism; Interleukin-2 Receptor alpha Subunit/immunology; Male; Middle Aged; T-Lymphocytes, Regulatory/physiology; T-Lymphocytes, Regulatory/transplantation; Transforming Growth Factor beta1/immunology; Transforming Growth Factor beta1/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colitis, Ulcerative / Cell Separation / Leukapheresis / T-Lymphocytes, Regulatory Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Cytotherapy Journal subject: TERAPEUTICA Year: 2008 Type: Article Affiliation country: Japan

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