Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity.

Dabovic, Branka; Chen, Yan; Choi, Jiwon; Vassallo, Melinda; Dietz, Harry C; Ramirez, Francesco; von Melchner, Harald; Davis, Elaine C; Rifkin, Daniel B

Dabovic, Branka; Chen, Yan; Choi, Jiwon; Vassallo, Melinda; Dietz, Harry C; Ramirez, Francesco; von Melchner, Harald; Davis, Elaine C; Rifkin, Daniel B.

Affiliation

Dabovic B; Department of Cell Biology, New York University School of Medicine, New York, New York, USA.

J Cell Physiol ; 219(1): 14-22, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19016471

Subject(s)

Elastin/metabolism; Latent TGF-beta Binding Proteins/metabolism; Lung/embryology; Lung/growth & development; Protein Isoforms/metabolism; Transforming Growth Factor beta/metabolism; Animals; Benzamides/metabolism; Dioxoles/metabolism; Elastin/genetics; Elastin/ultrastructure; Female; Latent TGF-beta Binding Proteins/genetics; Lung/anatomy & histology; Lung/metabolism; Male; Mice; Mice, Knockout; Phenotype; Pregnancy; Protein Isoforms/genetics; Protein Serine-Threonine Kinases/antagonists & inhibitors; Protein Serine-Threonine Kinases/metabolism; Pulmonary Alveoli/physiology; Pulmonary Alveoli/ultrastructure; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta/antagonists & inhibitors; Receptors, Transforming Growth Factor beta/metabolism; Signal Transduction/physiology; Transforming Growth Factor beta/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transforming Growth Factor beta / Elastin / Protein Isoforms / Latent TGF-beta Binding Proteins / Lung Limits: Animals / Pregnancy Language: En Journal: J Cell Physiol Year: 2009 Type: Article Affiliation country: United States

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