Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin.

Bu, Ye; Lu, Chunhua; Bian, Chunjing; Wang, Jinghua; Li, Jing; Zhang, Bin; Li, Zhenya; Brewer, Gary; Zhao, Robert Chunhua

Bu, Ye; Lu, Chunhua; Bian, Chunjing; Wang, Jinghua; Li, Jing; Zhang, Bin; Li, Zhenya; Brewer, Gary; Zhao, Robert Chunhua.

Affiliation

Bu Y; Center of Tissue Engineering, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, PR China.

Oncol Rep ; 21(1): 13-7, 2009 Jan.

Article in En | MEDLINE | ID: mdl-19082437

Subject(s)

Antineoplastic Agents/pharmacology; Breast Neoplasms/enzymology; Cisplatin/pharmacology; Drug Resistance, Neoplasm/genetics; Ribonuclease III/metabolism; Blotting, Western; Breast Neoplasms/genetics; Cell Line, Tumor; Cell Proliferation/drug effects; Cell Survival/drug effects; Cell Survival/genetics; Female; G1 Phase/genetics; Humans; MicroRNAs/metabolism; RNA, Small Interfering; Reverse Transcriptase Polymerase Chain Reaction; Ribonuclease III/genetics; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Cisplatin / Drug Resistance, Neoplasm / Ribonuclease III / Antineoplastic Agents Type of study: Diagnostic_studies Limits: Female / Humans Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2009 Type: Article

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