Up-regulation of connective tissue growth factor in endothelial cells by the microtubule-destabilizing agent combretastatin A-4.

Samarin, Jana; Rehm, Margot; Krueger, Bettina; Waschke, Jens; Goppelt-Struebe, Margarete

Samarin, Jana; Rehm, Margot; Krueger, Bettina; Waschke, Jens; Goppelt-Struebe, Margarete.

Affiliation

Samarin J; Department of Nephrology and Hypertension, University of Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany.

Mol Cancer Res ; 7(2): 180-8, 2009 Feb.

Article in En | MEDLINE | ID: mdl-19208742

Subject(s)

Antineoplastic Agents, Phytogenic/pharmacology; Connective Tissue Growth Factor/metabolism; Endothelium, Vascular/drug effects; Microtubules/drug effects; Stilbenes/pharmacology; Animals; Blotting, Western; Cells, Cultured; Colchicine/pharmacology; Connective Tissue Growth Factor/genetics; Endothelium, Vascular/metabolism; Forkhead Box Protein O1; Forkhead Transcription Factors/metabolism; Mice; Mitogen-Activated Protein Kinases/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt/antagonists & inhibitors; Proto-Oncogene Proteins c-akt/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction; Tubulin Modulators/pharmacology; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Endothelium, Vascular / Connective Tissue Growth Factor / Microtubules / Antineoplastic Agents, Phytogenic Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mol Cancer Res Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2009 Type: Article Affiliation country: Germany

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