STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1.

Park, Chan Young; Hoover, Paul J; Mullins, Franklin M; Bachhawat, Priti; Covington, Elizabeth D; Raunser, Stefan; Walz, Thomas; Garcia, K Christopher; Dolmetsch, Ricardo E; Lewis, Richard S

Park, Chan Young; Hoover, Paul J; Mullins, Franklin M; Bachhawat, Priti; Covington, Elizabeth D; Raunser, Stefan; Walz, Thomas; Garcia, K Christopher; Dolmetsch, Ricardo E; Lewis, Richard S.

Affiliation

Park CY; Department of Neurobiology, Stanford University School of Medicine, CA 94305, USA.

Cell ; 136(5): 876-90, 2009 Mar 06.

Article in En | MEDLINE | ID: mdl-19249086

Subject(s)

Calcium Channels/metabolism; Calcium Signaling; Membrane Proteins/metabolism; Neoplasm Proteins/metabolism; Calcium Channels/chemistry; Cell Line; Cell Membrane/metabolism; Endoplasmic Reticulum/metabolism; Humans; ORAI1 Protein; Protein Structure, Tertiary; Stromal Interaction Molecule 1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium Channels / Calcium Signaling / Membrane Proteins / Neoplasm Proteins Limits: Humans Language: En Journal: Cell Year: 2009 Type: Article Affiliation country: United States

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