Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain.

Beurel, Eléonore; Jope, Richard S

Beurel, Eléonore; Jope, Richard S.

Affiliation

Beurel E; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294-0017, USA. eleonore_beurel@hotmail.fr

J Neuroinflammation ; 6: 9, 2009 Mar 11.

Article in En | MEDLINE | ID: mdl-19284588

Subject(s)

Brain/physiology; Glycogen Synthase Kinase 3/metabolism; Interleukin-6/metabolism; Lipopolysaccharides/toxicity; STAT3 Transcription Factor/metabolism; Animals; Brain/drug effects; Cells, Cultured; Cytokines/blood; Cytokines/metabolism; Escherichia coli; Gene Knockdown Techniques; Glial Fibrillary Acidic Protein/metabolism; Glycogen Synthase Kinase 3/antagonists & inhibitors; Inflammation/chemically induced; Interleukin-6/blood; Lithium Compounds/metabolism; Male; Mice; Mice, Inbred C57BL; Neuroglia/drug effects; Neuroglia/physiology; Sepsis/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Lipopolysaccharides / Interleukin-6 / Glycogen Synthase Kinase 3 / STAT3 Transcription Factor Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2009 Type: Article Affiliation country: United States

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