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A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.
Chan, Joyce C Y; Piper, Derek E; Cao, Qiong; Liu, Dongming; King, Chadwick; Wang, Wei; Tang, Jie; Liu, Qiang; Higbee, Jared; Xia, Zhen; Di, Yongmei; Shetterly, Susan; Arimura, Ziva; Salomonis, Heather; Romanow, William G; Thibault, Stephen T; Zhang, Richard; Cao, Ping; Yang, Xiao-Ping; Yu, Timothy; Lu, Mei; Retter, Marc W; Kwon, Gayle; Henne, Kirk; Pan, Oscar; Tsai, Mei-Mei; Fuchslocher, Bryna; Yang, Evelyn; Zhou, Lei; Lee, Ki Jeong; Daris, Mark; Sheng, Jackie; Wang, Yan; Shen, Wenyan D; Yeh, Wen-Chen; Emery, Maurice; Walker, Nigel P C; Shan, Bei; Schwarz, Margrit; Jackson, Simon M.
Affiliation
  • Chan JC; Department of Metabolic Disorders, Amgen Inc., South San Francisco, CA 94080, USA.
Proc Natl Acad Sci U S A ; 106(24): 9820-5, 2009 Jun 16.
Article in En | MEDLINE | ID: mdl-19443683
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neutralization Tests / Serine Endopeptidases / Cholesterol / Antibodies, Monoclonal Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neutralization Tests / Serine Endopeptidases / Cholesterol / Antibodies, Monoclonal Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article Affiliation country: United States