High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue.

Tol, Jolien; Dijkstra, Jeroen R; Vink-Börger, Marianne E; Nagtegaal, Iris D; Punt, Cornelis J A; Van Krieken, Johan H J M; Ligtenberg, Marjolijn J L

Tol, Jolien; Dijkstra, Jeroen R; Vink-Börger, Marianne E; Nagtegaal, Iris D; Punt, Cornelis J A; Van Krieken, Johan H J M; Ligtenberg, Marjolijn J L.

Affiliation

Tol J; Department of Medical Oncology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands. J.Tol@aig.umcn.nl

J Cell Mol Med ; 14(8): 2122-31, 2010 Aug.

Article in En | MEDLINE | ID: mdl-19453520

Subject(s)

Colorectal Neoplasms/genetics; DNA Mutational Analysis/methods; Genes, ras/genetics; Mutation; Polymerase Chain Reaction/methods; Colorectal Neoplasms/diagnosis; DNA, Neoplasm/chemistry; DNA, Neoplasm/genetics; Gene Frequency; Genotype; Humans; Reproducibility of Results; Sensitivity and Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Mutational Analysis / Colorectal Neoplasms / Polymerase Chain Reaction / Genes, ras / Mutation Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2010 Type: Article Affiliation country: Netherlands

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