Essential role of cofilin-1 in regulating thrombin-induced RelA/p65 nuclear translocation and intercellular adhesion molecule 1 (ICAM-1) expression in endothelial cells.

Fazal, Fabeha; Bijli, Kaiser M; Minhajuddin, Mohd; Rein, Theo; Finkelstein, Jacob N; Rahman, Arshad

Fazal, Fabeha; Bijli, Kaiser M; Minhajuddin, Mohd; Rein, Theo; Finkelstein, Jacob N; Rahman, Arshad.

Affiliation

Fazal F; Department of Pediatrics (Neonatology), Lung Biology and Disease Program, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA. Fabeha_Fazal@urmc.rochester.edu

J Biol Chem ; 284(31): 21047-56, 2009 Jul 31.

Article in En | MEDLINE | ID: mdl-19483084

Subject(s)

Cell Nucleus/metabolism; Cofilin 1/metabolism; Endothelial Cells/drug effects; Endothelial Cells/metabolism; Intercellular Adhesion Molecule-1/metabolism; Thrombin/pharmacology; Transcription Factor RelA/metabolism; Cell Nucleus/drug effects; Endothelial Cells/cytology; Endothelial Cells/enzymology; Gene Knockdown Techniques; Humans; I-kappa B Proteins/metabolism; Intercellular Adhesion Molecule-1/genetics; Models, Biological; NF-KappaB Inhibitor alpha; Phosphorylation/drug effects; Promoter Regions, Genetic/genetics; Protein Kinase Inhibitors/pharmacology; Protein Processing, Post-Translational/drug effects; Protein Transport/drug effects; RNA Interference/drug effects; Stress Fibers/drug effects; Stress Fibers/metabolism; rho-Associated Kinases/antagonists & inhibitors; rhoA GTP-Binding Protein/metabolism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombin / Cell Nucleus / Intercellular Adhesion Molecule-1 / Endothelial Cells / Cofilin 1 / Transcription Factor RelA Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2009 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google