TH2 cytokines potently induce an appetite-stimulating peptide, melanin-concentrating hormone, in human vascular endothelial cells.

Orihara, Kanami; Morita, Hideaki; Yagami, Akiko; Kajiwara, Naoki; Nakae, Susumu; Matsumoto, Kenji; Nagasaki, Hiroshi; Saito, Yumiko; Saito, Hirohisa; Matsuda, Akio

Orihara, Kanami; Morita, Hideaki; Yagami, Akiko; Kajiwara, Naoki; Nakae, Susumu; Matsumoto, Kenji; Nagasaki, Hiroshi; Saito, Yumiko; Saito, Hirohisa; Matsuda, Akio.

J Allergy Clin Immunol ; 124(3): 612-4, 614.e1-2, 2009 Sep.

Article in En | MEDLINE | ID: mdl-19541358

Subject(s)

Appetite/genetics; Asthma/genetics; Cytokines/immunology; Endothelium, Vascular/immunology; Hypothalamic Hormones/genetics; Melanins/genetics; Obesity/complications; Pituitary Hormones/genetics; Th2 Cells/immunology; Animals; Appetite/immunology; Asthma/etiology; Chromosomes, Human, Pair 12/genetics; Cytokines/pharmacology; Endothelium, Vascular/drug effects; Gene Expression Profiling; Gene Silencing; Humans; Interleukin-4/immunology; Interleukin-4/pharmacology; Mice; RNA, Small Interfering/metabolism; STAT6 Transcription Factor/genetics; STAT6 Transcription Factor/metabolism; Th2 Cells/drug effects; Tumor Necrosis Factor-alpha/immunology; Tumor Necrosis Factor-alpha/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Appetite / Pituitary Hormones / Asthma / Endothelium, Vascular / Cytokines / Th2 Cells / Hypothalamic Hormones / Melanins / Obesity Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: J Allergy Clin Immunol Year: 2009 Type: Article

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