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Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation.
Song, Gang; Ouyang, Gaoliang; Mao, Yubin; Ming, Yanlin; Bao, Shideng; Hu, Tianhui.
Affiliation
  • Song G; Cancer Research Center, Xiamen University Medical College, Xiamen, China.
  • Ouyang G; The Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen, China.
  • Mao Y; The Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen, China.
  • Ming Y; Cancer Research Center, Xiamen University Medical College, Xiamen, China.
  • Bao S; The Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen, China.
  • Hu T; The Key Laboratory of Ministry of Education for Cell Biology and Tumor Cell Engineering, School of Life Sciences, Xiamen University, Xiamen, China.
J Cell Mol Med ; 13(8B): 1706-1718, 2009 Aug.
Article in En | MEDLINE | ID: mdl-19602039
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Up-Regulation / Cell Survival / Matrix Metalloproteinase 9 / Proto-Oncogene Proteins c-akt / Hypoxia-Inducible Factor 1, alpha Subunit / Osteopontin / Neoplasm Invasiveness / Neoplasm Metastasis Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2009 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stomach Neoplasms / Up-Regulation / Cell Survival / Matrix Metalloproteinase 9 / Proto-Oncogene Proteins c-akt / Hypoxia-Inducible Factor 1, alpha Subunit / Osteopontin / Neoplasm Invasiveness / Neoplasm Metastasis Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: J Cell Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2009 Type: Article Affiliation country: China