Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.

Wirth, Eva K; Roth, Stephan; Blechschmidt, Cristiane; Hölter, Sabine M; Becker, Lore; Racz, Ildiko; Zimmer, Andreas; Klopstock, Thomas; Gailus-Durner, Valerie; Fuchs, Helmut; Wurst, Wolfgang; Naumann, Thomas; Bräuer, Anja; de Angelis, Martin Hrabé; Köhrle, Josef; Grüters, Annette; Schweizer, Ulrich

Wirth, Eva K; Roth, Stephan; Blechschmidt, Cristiane; Hölter, Sabine M; Becker, Lore; Racz, Ildiko; Zimmer, Andreas; Klopstock, Thomas; Gailus-Durner, Valerie; Fuchs, Helmut; Wurst, Wolfgang; Naumann, Thomas; Bräuer, Anja; de Angelis, Martin Hrabé; Köhrle, Josef; Grüters, Annette; Schweizer, Ulrich.

Affiliation

Wirth EK; Neuroscience Research Center, Charité Universitätsmedizin Berlin, Berlin, Germany.

J Neurosci ; 29(30): 9439-49, 2009 Jul 29.

Article in En | MEDLINE | ID: mdl-19641107

Subject(s)

Behavior, Animal; Membrane Transport Proteins/deficiency; Mental Retardation, X-Linked/genetics; Neurons/physiology; Triiodothyronine/metabolism; Amino Acid Transport System y+/metabolism; Animals; Brain/embryology; Brain/growth & development; Brain/metabolism; Cells, Cultured; Fusion Regulatory Protein 1, Light Chains/metabolism; Humans; Hyperthyroidism/physiopathology; Hypothyroidism/physiopathology; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism; Mice; Mice, Knockout; Microglia/metabolism; Monocarboxylic Acid Transporters; Neuropsychological Tests; Phenotype; RNA, Messenger/metabolism; Symporters; Syndrome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Triiodothyronine / Behavior, Animal / Mental Retardation, X-Linked / Neurons Limits: Animals / Humans Language: En Journal: J Neurosci Year: 2009 Type: Article Affiliation country: Germany

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