The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification.

Koncarevic, Sasa; Rohrbach, Petra; Deponte, Marcel; Krohne, Georg; Prieto, Judith Helena; Yates, John; Rahlfs, Stefan; Becker, Katja

Koncarevic, Sasa; Rohrbach, Petra; Deponte, Marcel; Krohne, Georg; Prieto, Judith Helena; Yates, John; Rahlfs, Stefan; Becker, Katja.

Affiliation

Koncarevic S; Interdisciplinary Research Center, Heinrich-Buff-Ring 26-32, D-35392 Giessen, Germany.

Proc Natl Acad Sci U S A ; 106(32): 13323-8, 2009 Aug 11.

Article in En | MEDLINE | ID: mdl-19666612

Subject(s)

Inactivation, Metabolic; Malaria, Falciparum/parasitology; Peroxides/metabolism; Peroxiredoxins/metabolism; Plasmodium falciparum/metabolism; Animals; Carrier Proteins/metabolism; Cell Extracts; Chloroquine/pharmacology; Cytosol/drug effects; Cytosol/ultrastructure; Erythrocytes/cytology; Erythrocytes/drug effects; Erythrocytes/parasitology; Erythrocytes/ultrastructure; Fluorescent Antibody Technique; Green Fluorescent Proteins/metabolism; Hemoglobins/metabolism; Humans; Kinetics; Membrane Proteins/metabolism; Peroxiredoxins/ultrastructure; Plasmodium falciparum/cytology; Plasmodium falciparum/drug effects; Plasmodium falciparum/ultrastructure; Protein Transport/drug effects; Protozoan Proteins/metabolism; Vacuoles/drug effects; Vacuoles/metabolism; Vacuoles/ultrastructure

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peroxides / Plasmodium falciparum / Inactivation, Metabolic / Malaria, Falciparum / Peroxiredoxins Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Type: Article Affiliation country: Germany

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