Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter.

Cozzi, Nicholas V; Gopalakrishnan, Anupama; Anderson, Lyndsey L; Feih, Joel T; Shulgin, Alexander T; Daley, Paul F; Ruoho, Arnold E

Cozzi, Nicholas V; Gopalakrishnan, Anupama; Anderson, Lyndsey L; Feih, Joel T; Shulgin, Alexander T; Daley, Paul F; Ruoho, Arnold E.

Affiliation

Cozzi NV; Department of Pharmacology, University of Wisconsin School of Medicine and Public Health, 1300 University Avenue, Wisconsin, WI 53706, USA. cozzi@wisc.edu

J Neural Transm (Vienna) ; 116(12): 1591-9, 2009 Dec.

Article in En | MEDLINE | ID: mdl-19756361

Subject(s)

Hallucinogens/pharmacology; Serotonin Plasma Membrane Transport Proteins/chemistry; Tryptamines/pharmacology; Vesicular Monoamine Transport Proteins/chemistry; Animals; Blood Platelets/chemistry; Blood Platelets/drug effects; Blood Platelets/metabolism; Cell Line; Hallucinogens/chemistry; Hallucinogens/metabolism; Humans; N,N-Dimethyltryptamine/chemistry; N,N-Dimethyltryptamine/metabolism; N,N-Dimethyltryptamine/pharmacology; Paroxetine/chemistry; Paroxetine/metabolism; Paroxetine/pharmacology; Rats; Serotonin/chemistry; Serotonin/metabolism; Serotonin Plasma Membrane Transport Proteins/metabolism; Selective Serotonin Reuptake Inhibitors/chemistry; Selective Serotonin Reuptake Inhibitors/metabolism; Selective Serotonin Reuptake Inhibitors/pharmacology; Spodoptera; Tetrabenazine/analogs & derivatives; Tetrabenazine/chemistry; Tetrabenazine/metabolism; Tetrabenazine/pharmacology; Tritium; Tryptamines/chemistry; Tryptamines/metabolism; Vesicular Monoamine Transport Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tryptamines / Vesicular Monoamine Transport Proteins / Serotonin Plasma Membrane Transport Proteins / Hallucinogens Limits: Animals / Humans Language: En Journal: J Neural Transm (Vienna) Year: 2009 Type: Article Affiliation country: United States

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