Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells.

Idelson, Maria; Alper, Ruslana; Obolensky, Alexey; Ben-Shushan, Etti; Hemo, Itzhak; Yachimovich-Cohen, Nurit; Khaner, Hanita; Smith, Yoav; Wiser, Ofer; Gropp, Michal; Cohen, Malkiel A; Even-Ram, Sharona; Berman-Zaken, Yael; Matzrafi, Limor; Rechavi, Gideon; Banin, Eyal; Reubinoff, Benjamin

Idelson, Maria; Alper, Ruslana; Obolensky, Alexey; Ben-Shushan, Etti; Hemo, Itzhak; Yachimovich-Cohen, Nurit; Khaner, Hanita; Smith, Yoav; Wiser, Ofer; Gropp, Michal; Cohen, Malkiel A; Even-Ram, Sharona; Berman-Zaken, Yael; Matzrafi, Limor; Rechavi, Gideon; Banin, Eyal; Reubinoff, Benjamin.

Affiliation

Idelson M; The Hadassah Human Embryonic Stem Cell Research Center, The Goldyne Savad Institute of Gene Therapy & Department of Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Cell Stem Cell ; 5(4): 396-408, 2009 Oct 02.

Article in En | MEDLINE | ID: mdl-19796620

Subject(s)

Embryonic Stem Cells/cytology; Epithelial Cells/cytology; Retinal Pigment Epithelium/cytology; Activin Receptors, Type I/pharmacology; Activin Receptors, Type II/pharmacology; Activins/pharmacology; Animals; Cell Differentiation/drug effects; Cell Line; Cell Transplantation; Embryonic Stem Cells/drug effects; Embryonic Stem Cells/ultrastructure; Epithelial Cells/drug effects; Epithelial Cells/ultrastructure; Fibroblast Growth Factor 2/pharmacology; Flow Cytometry; Humans; Immunophenotyping; Microscopy, Electron, Transmission; Microscopy, Phase-Contrast; Polymerase Chain Reaction; Rats; Transforming Growth Factor beta/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Epithelial Cells / Embryonic Stem Cells / Retinal Pigment Epithelium Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2009 Type: Article Affiliation country: Israel

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