Diacylglycerol kinase delta and protein kinase C(alpha) modulate epidermal growth factor receptor abundance and degradation through ubiquitin-specific protease 8.

Cai, Jinjin; Crotty, Tracy M; Reichert, Ethan; Carraway, Kermit L; Stafforini, Diana M; Topham, Matthew K

Cai, Jinjin; Crotty, Tracy M; Reichert, Ethan; Carraway, Kermit L; Stafforini, Diana M; Topham, Matthew K.

Affiliation

Cai J; Huntsman Cancer Institute, Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 84112, USA.

J Biol Chem ; 285(10): 6952-9, 2010 Mar 05.

Article in En | MEDLINE | ID: mdl-20064931

Subject(s)

Diacylglycerol Kinase/metabolism; Endopeptidases/metabolism; Endosomal Sorting Complexes Required for Transport/metabolism; ErbB Receptors/metabolism; Protein Kinase C-alpha/metabolism; Ubiquitin Thiolesterase/metabolism; Animals; Cell Line, Tumor; Diacylglycerol Kinase/genetics; Endocytosis/physiology; Endopeptidases/genetics; Endosomal Sorting Complexes Required for Transport/genetics; Enzyme Activation; ErbB Receptors/genetics; HeLa Cells; Humans; Intracellular Signaling Peptides and Proteins/genetics; Intracellular Signaling Peptides and Proteins/metabolism; Lung Neoplasms/metabolism; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Protein Kinase C-alpha/genetics; Proto-Oncogene Proteins c-akt/genetics; Proto-Oncogene Proteins c-akt/metabolism; Proto-Oncogene Proteins c-cbl/genetics; Proto-Oncogene Proteins c-cbl/metabolism; RNA Interference; Ubiquitin Thiolesterase/genetics; Ubiquitinated Proteins/genetics; Ubiquitinated Proteins/metabolism; Ubiquitination

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endopeptidases / Diacylglycerol Kinase / Ubiquitin Thiolesterase / Protein Kinase C-alpha / Endosomal Sorting Complexes Required for Transport / ErbB Receptors Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: United States

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