Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents.

Georgia, Senta; Hinault, Charlotte; Kawamori, Dan; Hu, Jiang; Meyer, John; Kanji, Murtaza; Bhushan, Anil; Kulkarni, Rohit N

Georgia, Senta; Hinault, Charlotte; Kawamori, Dan; Hu, Jiang; Meyer, John; Kanji, Murtaza; Bhushan, Anil; Kulkarni, Rohit N.

Affiliation

Georgia S; Larry Hillblom Islet Research Center, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA.

Diabetes ; 59(4): 987-96, 2010 Apr.

Article in En | MEDLINE | ID: mdl-20103709

Subject(s)

Cyclin D2/pharmacology; Diabetes Mellitus, Experimental/genetics; Hyperglycemia/genetics; Insulin Resistance/physiology; Insulin-Secreting Cells/pathology; Receptor, Insulin/deficiency; Animals; Cyclin D1/genetics; Cyclin D2/deficiency; Cyclin D2/genetics; Genotype; Homozygote; Hyperplasia/physiopathology; Liver/physiology; Mice; Mice, Knockout; Receptor, Insulin/genetics; Reverse Transcriptase Polymerase Chain Reaction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Receptor, Insulin / Diabetes Mellitus, Experimental / Insulin-Secreting Cells / Cyclin D2 / Hyperglycemia Limits: Animals Language: En Journal: Diabetes Year: 2010 Type: Article Affiliation country: United States

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