The number of circulating recent thymic emigrants is severely reduced 1 year after a single dose of alemtuzumab in renal transplant recipients.

Scarsi, Mirko; Bossini, Nicola; Malacarne, Fabio; Valerio, Francesca; Sandrini, Silvio; Airò, Paolo

Scarsi, Mirko; Bossini, Nicola; Malacarne, Fabio; Valerio, Francesca; Sandrini, Silvio; Airò, Paolo.

Affiliation

Scarsi M; Rheumatology and Clinical Immunology, and Nephrology, Spedali Civili, Brescia, Italy.

Transpl Int ; 23(8): 786-95, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20136785

Subject(s)

Antibodies, Monoclonal/adverse effects; Antibodies, Neoplasm/adverse effects; Cell Movement/drug effects; Kidney Transplantation/immunology; Lymphopenia/chemically induced; T-Lymphocyte Subsets/cytology; Thymus Gland/cytology; Adult; Alemtuzumab; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm/administration & dosage; Antineoplastic Agents/administration & dosage; Antineoplastic Agents/adverse effects; Basiliximab; Biomarkers/metabolism; Cell Movement/immunology; Female; Humans; Immunophenotyping; Immunosuppressive Agents/administration & dosage; Leukocyte Reduction Procedures/methods; Lymphocyte Count; Male; Middle Aged; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; Recombinant Fusion Proteins/administration & dosage; T-Lymphocyte Subsets/drug effects; T-Lymphocyte Subsets/metabolism; Thymus Gland/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymus Gland / Cell Movement / T-Lymphocyte Subsets / Kidney Transplantation / Lymphopenia / Antibodies, Monoclonal / Antibodies, Neoplasm Type of study: Clinical_trials / Guideline Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Transpl Int Journal subject: TRANSPLANTE Year: 2010 Type: Article Affiliation country: Italy

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