SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.

Han, Yan; Huang, Chao; Sun, Xuxu; Xiang, Binggang; Wang, Ming; Yeh, Edward T H; Chen, Yuying; Li, Hui; Shi, Guiying; Cang, Hui; Sun, Yueping; Wang, Jian; Wang, Wei; Gao, Fei; Yi, Jing

Han, Yan; Huang, Chao; Sun, Xuxu; Xiang, Binggang; Wang, Ming; Yeh, Edward T H; Chen, Yuying; Li, Hui; Shi, Guiying; Cang, Hui; Sun, Yueping; Wang, Jian; Wang, Wei; Gao, Fei; Yi, Jing.

Affiliation

Han Y; Department of Cell Biology, Key Laboratory of the Education Ministry for Cell Differentiation and Apoptosis, Institutes of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

J Biol Chem ; 285(17): 12906-15, 2010 Apr 23.

Article in En | MEDLINE | ID: mdl-20181954

Subject(s)

Cell Proliferation; Cysteine Endopeptidases/metabolism; Nuclear Proteins/metabolism; Oxidative Stress; Small Ubiquitin-Related Modifier Proteins/metabolism; Transcription Factors/metabolism; Tumor Suppressor Proteins/metabolism; Ubiquitins/metabolism; Adenocarcinoma/genetics; Adenocarcinoma/metabolism; Animals; Colonic Neoplasms/genetics; Colonic Neoplasms/metabolism; Cysteine Endopeptidases/genetics; Dose-Response Relationship, Drug; Gene Knockdown Techniques; HeLa Cells; Humans; Hydrogen Peroxide/pharmacology; Mice; NIH 3T3 Cells; Nuclear Proteins/genetics; Oxidants/pharmacology; Promyelocytic Leukemia Protein; Protein Processing, Post-Translational; Small Ubiquitin-Related Modifier Proteins/genetics; Transcription Factors/genetics; Tumor Suppressor Proteins/genetics; Ubiquitins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Cysteine Endopeptidases / Nuclear Proteins / Ubiquitins / Oxidative Stress / Tumor Suppressor Proteins / Small Ubiquitin-Related Modifier Proteins / Cell Proliferation Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: China

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