Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells.

Niyonsaba, François; Ushio, Hiroko; Hara, Mutsuko; Yokoi, Hidenori; Tominaga, Mitsutoshi; Takamori, Kenji; Kajiwara, Naoki; Saito, Hirohisa; Nagaoka, Isao; Ogawa, Hideoki; Okumura, Ko

Niyonsaba, François; Ushio, Hiroko; Hara, Mutsuko; Yokoi, Hidenori; Tominaga, Mitsutoshi; Takamori, Kenji; Kajiwara, Naoki; Saito, Hirohisa; Nagaoka, Isao; Ogawa, Hideoki; Okumura, Ko.

Affiliation

Niyonsaba F; Atopy Allergy Research Center, Juntendo University School of Medicine, Tokyo, Japan. francois@juntendo.ac.jp

J Immunol ; 184(7): 3526-34, 2010 Apr 01.

Article in En | MEDLINE | ID: mdl-20190140

Subject(s)

Cathelicidins/immunology; Inflammation/immunology; Interleukins/metabolism; Mast Cells/metabolism; Skin/immunology; beta-Defensins/immunology; Animals; Blotting, Western; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Gene Expression; Gene Expression Regulation/immunology; Humans; Mast Cells/immunology; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin / Interleukins / Beta-Defensins / Cathelicidins / Inflammation / Mast Cells Limits: Animals / Humans Language: En Journal: J Immunol Year: 2010 Type: Article Affiliation country: Japan

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