Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.

Yogev, Ohad; Yogev, Orli; Singer, Esti; Shaulian, Eitan; Goldberg, Michal; Fox, Thomas D; Pines, Ophry

Yogev, Ohad; Yogev, Orli; Singer, Esti; Shaulian, Eitan; Goldberg, Michal; Fox, Thomas D; Pines, Ophry.

Affiliation

Yogev O; Department of Microbiology and Molecular Genetics, IMRIC, Faculty of Medicine, Hebrew University, Jerusalem, Israel.

PLoS Biol ; 8(3): e1000328, 2010 Mar 09.

Article in En | MEDLINE | ID: mdl-20231875

Subject(s)

Cell Nucleus/metabolism; Cytosol/metabolism; DNA Damage; Fumarate Hydratase/metabolism; Isoenzymes/metabolism; Mitochondria/enzymology; Fumarate Hydratase/genetics; Fumarates/metabolism; Gene Knockdown Techniques; HeLa Cells; Histones/genetics; Histones/metabolism; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Isoenzymes/genetics; Kidney Neoplasms/enzymology; Kidney Neoplasms/genetics; Leiomyomatosis/enzymology; Leiomyomatosis/genetics; Saccharomyces cerevisiae/enzymology; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae Proteins/genetics; Saccharomyces cerevisiae Proteins/metabolism; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Cell Nucleus / Cytosol / Fumarate Hydratase / Isoenzymes / Mitochondria Limits: Humans Language: En Journal: PLoS Biol Journal subject: BIOLOGIA Year: 2010 Type: Article Affiliation country: Israel

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