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IL-1 and Allergy.
Nambu, Aya; Nakae, Susumu.
Affiliation
  • Nambu A; Atopy Research Center, Juntendo University, Tokyo, Japan.
Allergol Int ; 59(2): 125-35, 2010 Jun.
Article in En | MEDLINE | ID: mdl-20414049
ABSTRACT
IL-1 is a well-characterized proinflammatory cytokine that is involved in host defense and autoimmune diseases. IL-1 can promote activation of T cells, including Th1 cells, Th2 cells and Th17 cells, and B cells, suggesting that IL-1 may contribute to the development of various types of T-cell-mediated diseases. This report reviews and discusses the role of IL-1 in the pathogenesis of allergic diseases based on studies using IL-1-related gene-deficient mice.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Interleukin-1 / Hypersensitivity Limits: Animals / Humans Language: En Journal: Allergol Int Journal subject: ALERGIA E IMUNOLOGIA Year: 2010 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Interleukin-1 / Hypersensitivity Limits: Animals / Humans Language: En Journal: Allergol Int Journal subject: ALERGIA E IMUNOLOGIA Year: 2010 Type: Article Affiliation country: Japan