Mutation of Eif4g3, encoding a eukaryotic translation initiation factor, causes male infertility and meiotic arrest of mouse spermatocytes.

Sun, Fengyun; Palmer, Kristina; Handel, Mary Ann

Sun, Fengyun; Palmer, Kristina; Handel, Mary Ann.

Affiliation

Sun F; The Jackson Laboratory, Bar Harbor, ME 04609, USA.

Development ; 137(10): 1699-707, 2010 May.

Article in En | MEDLINE | ID: mdl-20430745

Subject(s)

Eukaryotic Initiation Factor-4G/genetics; Infertility, Male/genetics; Meiosis/genetics; Mutation, Missense/physiology; Spermatocytes/metabolism; Animals; Cell Division/genetics; Cell Proliferation; Eukaryotic Initiation Factor-4G/metabolism; Eukaryotic Initiation Factor-4G/physiology; Gene Expression Regulation, Developmental; HSP70 Heat-Shock Proteins/genetics; HSP70 Heat-Shock Proteins/metabolism; Male; Mice; Mice, Congenic; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Spermatocytes/physiology; Spermatogenesis/genetics; Spermatogenesis/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spermatocytes / Mutation, Missense / Eukaryotic Initiation Factor-4G / Infertility, Male / Meiosis Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2010 Type: Article Affiliation country: United States

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