Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition.

Raska, Milan; Takahashi, Kazuo; Czernekova, Lydie; Zachova, Katerina; Hall, Stacy; Moldoveanu, Zina; Elliott, Matt C; Wilson, Landon; Brown, Rhubell; Jancova, Dagmar; Barnes, Stephen; Vrbkova, Jana; Tomana, Milan; Smith, Phillip D; Mestecky, Jiri; Renfrow, Matthew B; Novak, Jan

Raska, Milan; Takahashi, Kazuo; Czernekova, Lydie; Zachova, Katerina; Hall, Stacy; Moldoveanu, Zina; Elliott, Matt C; Wilson, Landon; Brown, Rhubell; Jancova, Dagmar; Barnes, Stephen; Vrbkova, Jana; Tomana, Milan; Smith, Phillip D; Mestecky, Jiri; Renfrow, Matthew B; Novak, Jan.

Affiliation

Raska M; Department of Immunology, Palacky University in Olomouc, Olomouc 77100, Czech Republic. raskamil@uab.edu

J Biol Chem ; 285(27): 20860-9, 2010 Jul 02.

Article in En | MEDLINE | ID: mdl-20439465

Subject(s)

Antibodies/immunology; HIV Envelope Protein gp120/immunology; HIV Envelope Protein gp120/metabolism; Acquired Immunodeficiency Syndrome/immunology; Antibody Specificity; Cell Line; Cell Line, Tumor; DNA, Complementary/genetics; Enzyme-Linked Immunosorbent Assay/methods; Glycoside Hydrolases/metabolism; Glycosylation; HIV Envelope Protein gp120/genetics; HIV Envelope Protein gp120/isolation & purification; HIV Seropositivity/immunology; HIV Seropositivity/metabolism; HIV-1/immunology; HIV-1/metabolism; Hep G2 Cells/metabolism; Humans; Jurkat Cells/metabolism; Mannose/metabolism; Mannose-Binding Lectin/genetics; Mass Spectrometry; Oligosaccharides/chemistry; Oligosaccharides/isolation & purification; Plasmids; Polysaccharides/chemistry; Polysaccharides/isolation & purification

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Envelope Protein gp120 / Antibodies Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: Czech Republic

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