Diadenosine homodinucleotide products of ADP-ribosyl cyclases behave as modulators of the purinergic receptor P2X7.

Bruzzone, Santina; Basile, Giovanna; Chothi, Madhu Parakkottil; Nobbio, Lucilla; Usai, Cesare; Jacchetti, Emanuela; Schenone, Angelo; Guse, Andreas H; Di Virgilio, Francesco; De Flora, Antonio; Zocchi, Elena

Bruzzone, Santina; Basile, Giovanna; Chothi, Madhu Parakkottil; Nobbio, Lucilla; Usai, Cesare; Jacchetti, Emanuela; Schenone, Angelo; Guse, Andreas H; Di Virgilio, Francesco; De Flora, Antonio; Zocchi, Elena.

Affiliation

Bruzzone S; Department of Experimental Medicine, Section of Biochemistry, and Center of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV/1, 16132 Genova, Italy. santina.bruzzone@unige.it

J Biol Chem ; 285(27): 21165-74, 2010 Jul 02.

Article in En | MEDLINE | ID: mdl-20439466

Subject(s)

ADP-ribosyl Cyclase/metabolism; Receptors, Purinergic P2/physiology; ADP-ribosyl Cyclase 1/metabolism; Animals; Calcium/metabolism; Cell Division; Cell Line; Cell Survival/drug effects; Embryo, Mammalian; Ethidium/metabolism; Gadolinium/pharmacology; HeLa Cells/cytology; HeLa Cells/drug effects; HeLa Cells/metabolism; Humans; Invertebrates; Kidney/cytology; Kidney/drug effects; Kidney/enzymology; Kidney/physiology; Membrane Potential, Mitochondrial/physiology; Porifera/enzymology; Rats; Receptors, Purinergic P2X7; Transfection; Vertebrates

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Purinergic P2 / ADP-ribosyl Cyclase Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: Italy

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