Development of new localized drug delivery system based on ceftriaxone-sulbactam composite drug impregnated porous hydroxyapatite: a systematic approach for in vitro and in vivo animal trial.

Kundu, Biswanath; Soundrapandian, Chidambaram; Nandi, Samit K; Mukherjee, Prasenjit; Dandapat, Nandadulal; Roy, Subhasis; Datta, Bakul K; Mandal, Tapan K; Basu, Debabrata; Bhattacharya, Rupnarayan N

Kundu, Biswanath; Soundrapandian, Chidambaram; Nandi, Samit K; Mukherjee, Prasenjit; Dandapat, Nandadulal; Roy, Subhasis; Datta, Bakul K; Mandal, Tapan K; Basu, Debabrata; Bhattacharya, Rupnarayan N.

Affiliation

Kundu B; Bioceramics and Coating Division, Central Glass and Ceramic Research Institute, Kolkata, India. biswa_kundu@rediffmail.com

Pharm Res ; 27(8): 1659-76, 2010 Aug.

Article in En | MEDLINE | ID: mdl-20464462

Subject(s)

Anti-Bacterial Agents/administration & dosage; Ceftriaxone/administration & dosage; Disease Models, Animal; Drug Delivery Systems; Durapatite/chemical synthesis; Osteomyelitis/drug therapy; Sulbactam/administration & dosage; Animals; Anti-Bacterial Agents/pharmacology; Drug Compounding; Durapatite/administration & dosage; Durapatite/pharmacology; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Porosity; Powders; Rabbits; Staphylococcus aureus/drug effects; X-Ray Diffraction

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteomyelitis / Ceftriaxone / Sulbactam / Drug Delivery Systems / Durapatite / Disease Models, Animal / Anti-Bacterial Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pharm Res Year: 2010 Type: Article Affiliation country: India

Fulltext

XML

PubMed Links

Search on Google