Modulation of multidrug resistance p-glycoprotein activity by flavonoids and honokiol in human doxorubicin- resistant sarcoma cells (MES-SA/DX-5): implications for natural sedatives as chemosensitizing agents in cancer therapy.

Angelini, Aantonio; Di Ilio, C; Castellani, M L; Conti, P; Cuccurullo, F

Angelini, Aantonio; Di Ilio, C; Castellani, M L; Conti, P; Cuccurullo, F.

Affiliation

Angelini A; Department of Medicine and Aging, School of Medicine and Aging Research Center, Ce.S.I. G. d'Annunzio University Foundation, Chieti-Pescara, Italy. aangelini@unich.it

J Biol Regul Homeost Agents ; 24(2): 197-205, 2010.

Article in En | MEDLINE | ID: mdl-20487633

Subject(s)

Biphenyl Compounds/therapeutic use; Doxorubicin/therapeutic use; Drug Resistance, Multiple; Drugs, Chinese Herbal/therapeutic use; Flavonoids/therapeutic use; Hypnotics and Sedatives/therapeutic use; Lignans/therapeutic use; Sarcoma/drug therapy; Antibiotics, Antineoplastic/metabolism; Antibiotics, Antineoplastic/therapeutic use; Cell Division/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Doxorubicin/metabolism; Drug Resistance, Neoplasm; Glutathione/metabolism; Humans; Reactive Oxygen Species/metabolism; Sarcoma/pathology

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Sarcoma / Flavonoids / Biphenyl Compounds / Drugs, Chinese Herbal / Doxorubicin / Lignans / Drug Resistance, Multiple / Hypnotics and Sedatives Limits: Humans Language: En Journal: J Biol Regul Homeost Agents Journal subject: BIOLOGIA / BIOQUIMICA Year: 2010 Type: Article Affiliation country: Italy

Search on Google

XML

PubMed Links