Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.

Abbas, Saman; Lugthart, Sanne; Kavelaars, François G; Schelen, Anita; Koenders, Jasper E; Zeilemaker, Annelieke; van Putten, Wim J L; Rijneveld, Anita W; Löwenberg, Bob; Valk, Peter J M

Abbas, Saman; Lugthart, Sanne; Kavelaars, François G; Schelen, Anita; Koenders, Jasper E; Zeilemaker, Annelieke; van Putten, Wim J L; Rijneveld, Anita W; Löwenberg, Bob; Valk, Peter J M.

Affiliation

Abbas S; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Blood ; 116(12): 2122-6, 2010 Sep 23.

Article in En | MEDLINE | ID: mdl-20538800

Subject(s)

Isocitrate Dehydrogenase/genetics; Leukemia, Myeloid, Acute/genetics; Mutation; Adolescent; Adult; Aged; Female; Hematologic Diseases; Humans; Janus Kinase 2/genetics; Leukemia, Myeloid, Acute/classification; Male; Middle Aged; Nucleophosmin; Prevalence; Prognosis; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Isocitrate Dehydrogenase / Mutation Type of study: Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Blood Year: 2010 Type: Article Affiliation country: Netherlands

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