ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.

Pereira, Carlos F; Piccolo, Francesco M; Tsubouchi, Tomomi; Sauer, Stephan; Ryan, Natalie K; Bruno, Ludovica; Landeira, David; Santos, Joana; Banito, Ana; Gil, Jesus; Koseki, Haruhiko; Merkenschlager, Matthias; Fisher, Amanda G

Pereira, Carlos F; Piccolo, Francesco M; Tsubouchi, Tomomi; Sauer, Stephan; Ryan, Natalie K; Bruno, Ludovica; Landeira, David; Santos, Joana; Banito, Ana; Gil, Jesus; Koseki, Haruhiko; Merkenschlager, Matthias; Fisher, Amanda G.

Affiliation

Pereira CF; MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, UK.

Cell Stem Cell ; 6(6): 547-56, 2010 Jun 04.

Article in En | MEDLINE | ID: mdl-20569692

Subject(s)

B-Lymphocytes/metabolism; Embryonic Stem Cells/metabolism; Histone-Lysine N-Methyltransferase/metabolism; Induced Pluripotent Stem Cells/metabolism; Neoplastic Stem Cells/metabolism; Repressor Proteins/metabolism; Animals; Antigens, Differentiation/biosynthesis; Antigens, Differentiation/genetics; B-Lymphocytes/pathology; Cell Fusion; Cell Line, Transformed; Cellular Reprogramming/genetics; Embryonic Stem Cells/pathology; Gene Knockout Techniques; Histone-Lysine N-Methyltransferase/genetics; Humans; Induced Pluripotent Stem Cells/pathology; Mice; Neoplastic Stem Cells/pathology; Polycomb Repressive Complex 2; Polycomb-Group Proteins; Repressor Proteins/genetics; Telomerase/biosynthesis; Telomerase/genetics; Transcription Factors/biosynthesis; Transcription Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / Neoplastic Stem Cells / B-Lymphocytes / Histone-Lysine N-Methyltransferase / Embryonic Stem Cells / Induced Pluripotent Stem Cells Limits: Animals / Humans Language: En Journal: Cell Stem Cell Year: 2010 Type: Article Affiliation country: United kingdom

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