Intracoronary shear-related up-regulation of platelet P-selectin and platelet-monocyte aggregation despite the use of aspirin and clopidogrel.

Yong, Andy S C; Pennings, Gabrielle J; Chang, Michael; Hamzah, Afiqah; Chung, Tommy; Qi, Miao; Brieger, David; Behnia, Masud; Krilis, Steven A; Ng, Martin K C; Lowe, Harry C; Kritharides, Leonard

Yong, Andy S C; Pennings, Gabrielle J; Chang, Michael; Hamzah, Afiqah; Chung, Tommy; Qi, Miao; Brieger, David; Behnia, Masud; Krilis, Steven A; Ng, Martin K C; Lowe, Harry C; Kritharides, Leonard.

Affiliation

Yong AS; ANZAC Research Institute, University of Sydney, Sydney, Australia.

Blood ; 117(1): 11-20, 2011 Jan 06.

Article in En | MEDLINE | ID: mdl-20876457

Subject(s)

Aspirin/pharmacology; Blood Platelets/drug effects; Coronary Artery Disease/metabolism; Coronary Stenosis/metabolism; Monocytes/drug effects; P-Selectin/metabolism; Platelet Aggregation/drug effects; Ticlopidine/analogs & derivatives; Aged; Blood Platelets/metabolism; CD11b Antigen/metabolism; Clopidogrel; Coronary Artery Disease/drug therapy; Coronary Artery Disease/pathology; Coronary Stenosis/drug therapy; Coronary Stenosis/pathology; Flow Cytometry; Humans; Leukocytes/drug effects; Leukocytes/pathology; Monocytes/metabolism; Monocytes/pathology; Platelet Aggregation Inhibitors/pharmacology; Ticlopidine/pharmacology; Up-Regulation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Platelets / Coronary Artery Disease / Ticlopidine / Monocytes / Platelet Aggregation / Aspirin / P-Selectin / Coronary Stenosis Limits: Aged / Humans Language: En Journal: Blood Year: 2011 Type: Article Affiliation country: Australia

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