The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus.

Wang, Ying-Nai; Yamaguchi, Hirohito; Huo, Longfei; Du, Yi; Lee, Hong-Jen; Lee, Heng-Huan; Wang, Hongmei; Hsu, Jung-Mao; Hung, Mien-Chie

Wang, Ying-Nai; Yamaguchi, Hirohito; Huo, Longfei; Du, Yi; Lee, Hong-Jen; Lee, Heng-Huan; Wang, Hongmei; Hsu, Jung-Mao; Hung, Mien-Chie.

Affiliation

Wang YN; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

J Biol Chem ; 285(49): 38720-9, 2010 Dec 03.

Article in En | MEDLINE | ID: mdl-20937808

Subject(s)

ErbB Receptors/metabolism; Membrane Proteins/metabolism; Nuclear Pore/metabolism; Active Transport, Cell Nucleus/physiology; Cell Line, Tumor; ErbB Receptors/genetics; Gene Knockdown Techniques; Humans; Membrane Proteins/genetics; Nuclear Pore/genetics; Receptor, ErbB-2/genetics; Receptor, ErbB-2/metabolism; SEC Translocation Channels; beta Karyopherins/genetics; beta Karyopherins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nuclear Pore / ErbB Receptors / Membrane Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2010 Type: Article Affiliation country: United States

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