Alleviation of the acute doxorubicin-induced cardiotoxicity by Lycium barbarum polysaccharides through the suppression of oxidative stress.

Xin, Yan-Fei; Wan, Li-Li; Peng, Jin-Liang; Guo, Cheng

Xin, Yan-Fei; Wan, Li-Li; Peng, Jin-Liang; Guo, Cheng.

Affiliation

Xin YF; Center of Safety Evaluation, Zhejiang Academy of Medical Sciences, Hangzhou, Zhejiang, China.

Food Chem Toxicol ; 49(1): 259-64, 2011 Jan.

Article in En | MEDLINE | ID: mdl-21056614

Subject(s)

Antineoplastic Agents/antagonists & inhibitors; Doxorubicin/antagonists & inhibitors; Drugs, Chinese Herbal/pharmacology; Heart/drug effects; Lycium/chemistry; Oxidative Stress/drug effects; Animals; Antineoplastic Agents/toxicity; Body Weight/drug effects; Doxorubicin/toxicity; Electrocardiography; Glutathione Peroxidase/metabolism; Male; Malondialdehyde/metabolism; Myocardium/enzymology; Myocardium/metabolism; Organ Size/drug effects; Rats; Rats, Sprague-Dawley; Superoxide Dismutase/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drugs, Chinese Herbal / Doxorubicin / Oxidative Stress / Lycium / Heart / Antineoplastic Agents Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2011 Type: Article Affiliation country: China

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