Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.

Limbo, Oliver; Porter-Goff, Mary E; Rhind, Nicholas; Russell, Paul

Limbo, Oliver; Porter-Goff, Mary E; Rhind, Nicholas; Russell, Paul.

Affiliation

Limbo O; Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037, USA.

Mol Cell Biol ; 31(3): 573-83, 2011 Feb.

Article in En | MEDLINE | ID: mdl-21098122

Subject(s)

DNA Breaks, Double-Stranded; Schizosaccharomyces pombe Proteins/metabolism; Schizosaccharomyces/enzymology; Cell Cycle Proteins/metabolism; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA-Binding Proteins/metabolism; Endodeoxyribonucleases/metabolism; Enzyme Activation; Gene Deletion; Humans; Models, Biological; Phosphorylation; Protein Binding; Protein Kinases/metabolism; Protein Serine-Threonine Kinases/metabolism; Schizosaccharomyces/cytology; Signal Transduction; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizosaccharomyces / Schizosaccharomyces pombe Proteins / DNA Breaks, Double-Stranded Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Biol Year: 2011 Type: Article Affiliation country: United States

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