[Growth dynamics of transplantable murine tumors in the course of dicarbamin-protected chemotherapy].
Vopr Onkol
; 56(5): 591-2, 594-6, 2010.
Article
in Ru
| MEDLINE
| ID: mdl-21137241
ABSTRACT
Dicarbamin-assisted mono- and combination chemotherapy (cyclophosphamide + carboplatin + cisplatin) for transplantable tumors born by linear or hybrid mice of both sexes was investigated. It was shown that long-term oral administration contributed to the effect of a range of cytostatic therapeutic dosage rather than adversely affected it. Our findings were used to make a case for clinical studies of dicarbamin for its potential of lowering hematological toxicity of antitumor therapy.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Protective Agents
/
Hematologic Diseases
/
Imidazoles
/
Neoplasms
/
Antineoplastic Agents
Limits:
Animals
Language:
Ru
Journal:
Vopr Onkol
Year:
2010
Type:
Article