Systemic human Netrin-1 gene delivery by adeno-associated virus type 8 alters leukocyte accumulation and atherogenesis in vivo.

Khan, J A; Cao, M; Kang, B Y; Liu, Y; Mehta, J L; Hermonat, P L

Khan, J A; Cao, M; Kang, B Y; Liu, Y; Mehta, J L; Hermonat, P L.

Affiliation

Khan JA; Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.

Gene Ther ; 18(5): 437-44, 2011 May.

Article in En | MEDLINE | ID: mdl-21160531

Subject(s)

Dependovirus/genetics; Genetic Therapy/methods; Leukocytes/immunology; Nerve Growth Factors/genetics; Plaque, Atherosclerotic/prevention & control; Tumor Suppressor Proteins/genetics; Animals; Aorta/pathology; Blood Flow Velocity; CD8-Positive T-Lymphocytes/immunology; Cholesterol/blood; Gene Transfer Techniques; Inflammation/prevention & control; Mice; Mice, Knockout; Netrin-1; Plaque, Atherosclerotic/immunology; Plaque, Atherosclerotic/pathology; Receptors, LDL/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Dependovirus / Tumor Suppressor Proteins / Plaque, Atherosclerotic / Leukocytes / Nerve Growth Factors Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2011 Type: Article Affiliation country: United States

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