The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.

Tochowicz, Anna; Goettig, Peter; Evans, Richard; Visse, Robert; Shitomi, Yasuyuki; Palmisano, Ralf; Ito, Noriko; Richter, Klaus; Maskos, Klaus; Franke, Daniel; Svergun, Dmitri; Nagase, Hideaki; Bode, Wolfram; Itoh, Yoshifumi

Tochowicz, Anna; Goettig, Peter; Evans, Richard; Visse, Robert; Shitomi, Yasuyuki; Palmisano, Ralf; Ito, Noriko; Richter, Klaus; Maskos, Klaus; Franke, Daniel; Svergun, Dmitri; Nagase, Hideaki; Bode, Wolfram; Itoh, Yoshifumi.

Affiliation

Tochowicz A; Arbeitsgruppe Proteinaseforschung, Max-Planck-Institut fuer Biochemie, Am Klopferspitz 18, D-82152 Martinsried, Germany.

J Biol Chem ; 286(9): 7587-600, 2011 Mar 04.

Article in En | MEDLINE | ID: mdl-21193411

Subject(s)

Extracellular Matrix/enzymology; Hemopexin/chemistry; Hemopexin/metabolism; Matrix Metalloproteinase 14/chemistry; Matrix Metalloproteinase 14/metabolism; Animals; COS Cells; Chlorocebus aethiops; Crystallography; Dimerization; Enzyme Activation/physiology; HeLa Cells; Hemopexin/genetics; Humans; Matrix Metalloproteinase 14/genetics; Membrane Proteins/chemistry; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mutagenesis; Protein Structure, Tertiary; Solubility; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hemopexin / Extracellular Matrix / Matrix Metalloproteinase 14 Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2011 Type: Article Affiliation country: Germany

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