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Potent and selective cyclohexyl-derived imidazopyrazine insulin-like growth factor 1 receptor inhibitors with in vivo efficacy.
Jin, Meizhong; Kleinberg, Andrew; Cooke, Andy; Gokhale, Prafulla C; Foreman, Kenneth; Dong, Hanqing; Siu, Kam W; Bittner, Mark A; Mulvihill, Kristen M; Yao, Yan; Landfair, Darla; O'Connor, Matthew; Mak, Gilda; Pachter, Jonathan A; Wild, Robert; Rosenfeld-Franklin, Maryland; Ji, Qunsheng; Mulvihill, Mark J.
Affiliation
  • Jin M; (OSI) Oncology, OSI Pharmaceuticals, Inc., 1 Bioscience Park Drive, Farmingdale, NY 11735, USA. mjin@osip.com
Bioorg Med Chem Lett ; 21(4): 1176-80, 2011 Feb 15.
Article in En | MEDLINE | ID: mdl-21251824
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazines / Benzimidazoles / Receptor, IGF Type 1 / Protein Kinase Inhibitors / Imidazoles / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazines / Benzimidazoles / Receptor, IGF Type 1 / Protein Kinase Inhibitors / Imidazoles / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2011 Type: Article Affiliation country: United States